Task 2.1 Patient Recruitment
In order to perform a multi-center, prospective clinical study we will recruit a total cohort of approximately 1200 participants (with approximately equal gender and pediatric/adults representations) out of which 830 patients with mild to severe community acquired LRTI, 220 with severe sepsis or septic shock and approximately 150 age-matched healthy controls .
Task 2.2 Patient Characterization
A data-minable electronic case report form (eCRF) will be constructed to record the patient clinical investigations, medical history, microbiological, radiological, and laboratory data.
Task 2.3 Sample Collection and Management